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mx 2401 penicillin  (ATCC)
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ATCC mx 2401 penicillin
Plasma <t>MX-2401</t> concentrations after single s.c. administrations of MX-2401 at 2.5, 10, and 40 mg/kg to neutropenic infected mice. The error bars represent standard deviations.
Mx 2401 Penicillin, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Plasma MX-2401 concentrations after single s.c. administrations of MX-2401 at 2.5, 10, and 40 mg/kg to neutropenic infected mice. The error bars represent standard deviations.

Journal: Antimicrobial Agents and Chemotherapy

Article Title: In Vivo Pharmacodynamics of New Lipopeptide MX-2401 ▿

doi: 10.1128/AAC.00238-10

Figure Lengend Snippet: Plasma MX-2401 concentrations after single s.c. administrations of MX-2401 at 2.5, 10, and 40 mg/kg to neutropenic infected mice. The error bars represent standard deviations.

Article Snippet: The MICs were 2- to 8-fold lower for pneumococci than for staphylococci. table ft1 table-wrap mode="anchored" t5 TABLE 1. caption a7 Study organism MIC (μg/ml) MX-2401 Penicillin a S. aureus ATCC 29213 2.0 0.5 (MSSA) ATCC 33591 2.0 R (MRSA) ATCC 6538P 1.0 0.12 (MSSA) UW 31005 2.0 R (MSSA) UW 307109 2.0 R (MRSA) S. pneumoniae ATCC 10813 0.25 0.008 (PSSP) CDC 1020 0.5 2.0 (PRSP) CDC 1199 0.25 1.0 (PRSP) CDC 1329 0.25 2.0 (PRSP) CDC 146 0.5 4.0 (PSRP) Open in a separate window a PSSP, penicillin-susceptible S. pneumoniae ; PRSP, penicillin-resistant S. pneumoniae .

Techniques: Infection

Killing and regrowth of S. pneumoniae ATCC 10813 (A), S. aureus ATCC 29213 (B), and S. aureus ATCC 33591 (C) over time in the thighs of neutropenic mice after exposure to a single s.c. dose of MX-2401. The error bars represent standard deviations.

Journal: Antimicrobial Agents and Chemotherapy

Article Title: In Vivo Pharmacodynamics of New Lipopeptide MX-2401 ▿

doi: 10.1128/AAC.00238-10

Figure Lengend Snippet: Killing and regrowth of S. pneumoniae ATCC 10813 (A), S. aureus ATCC 29213 (B), and S. aureus ATCC 33591 (C) over time in the thighs of neutropenic mice after exposure to a single s.c. dose of MX-2401. The error bars represent standard deviations.

Article Snippet: The MICs were 2- to 8-fold lower for pneumococci than for staphylococci. table ft1 table-wrap mode="anchored" t5 TABLE 1. caption a7 Study organism MIC (μg/ml) MX-2401 Penicillin a S. aureus ATCC 29213 2.0 0.5 (MSSA) ATCC 33591 2.0 R (MRSA) ATCC 6538P 1.0 0.12 (MSSA) UW 31005 2.0 R (MSSA) UW 307109 2.0 R (MRSA) S. pneumoniae ATCC 10813 0.25 0.008 (PSSP) CDC 1020 0.5 2.0 (PRSP) CDC 1199 0.25 1.0 (PRSP) CDC 1329 0.25 2.0 (PRSP) CDC 146 0.5 4.0 (PSRP) Open in a separate window a PSSP, penicillin-susceptible S. pneumoniae ; PRSP, penicillin-resistant S. pneumoniae .

Techniques:

Relationship between PK/PD indices for MX-2401 and efficacy against S. pneumoniae ATCC 10813 (A) and S. aureus ATCC 29213 (B) in the thighs of neutropenic mice.

Journal: Antimicrobial Agents and Chemotherapy

Article Title: In Vivo Pharmacodynamics of New Lipopeptide MX-2401 ▿

doi: 10.1128/AAC.00238-10

Figure Lengend Snippet: Relationship between PK/PD indices for MX-2401 and efficacy against S. pneumoniae ATCC 10813 (A) and S. aureus ATCC 29213 (B) in the thighs of neutropenic mice.

Article Snippet: The MICs were 2- to 8-fold lower for pneumococci than for staphylococci. table ft1 table-wrap mode="anchored" t5 TABLE 1. caption a7 Study organism MIC (μg/ml) MX-2401 Penicillin a S. aureus ATCC 29213 2.0 0.5 (MSSA) ATCC 33591 2.0 R (MRSA) ATCC 6538P 1.0 0.12 (MSSA) UW 31005 2.0 R (MSSA) UW 307109 2.0 R (MRSA) S. pneumoniae ATCC 10813 0.25 0.008 (PSSP) CDC 1020 0.5 2.0 (PRSP) CDC 1199 0.25 1.0 (PRSP) CDC 1329 0.25 2.0 (PRSP) CDC 146 0.5 4.0 (PSRP) Open in a separate window a PSSP, penicillin-susceptible S. pneumoniae ; PRSP, penicillin-resistant S. pneumoniae .

Techniques:

Dose-response relationships for MX-2401 against multiple strains of S. pneumoniae and S. aureus in the thighs of neutropenic mice. Each point represents the mean of 3 mice. The error bars represent standard deviations.

Journal: Antimicrobial Agents and Chemotherapy

Article Title: In Vivo Pharmacodynamics of New Lipopeptide MX-2401 ▿

doi: 10.1128/AAC.00238-10

Figure Lengend Snippet: Dose-response relationships for MX-2401 against multiple strains of S. pneumoniae and S. aureus in the thighs of neutropenic mice. Each point represents the mean of 3 mice. The error bars represent standard deviations.

Article Snippet: The MICs were 2- to 8-fold lower for pneumococci than for staphylococci. table ft1 table-wrap mode="anchored" t5 TABLE 1. caption a7 Study organism MIC (μg/ml) MX-2401 Penicillin a S. aureus ATCC 29213 2.0 0.5 (MSSA) ATCC 33591 2.0 R (MRSA) ATCC 6538P 1.0 0.12 (MSSA) UW 31005 2.0 R (MSSA) UW 307109 2.0 R (MRSA) S. pneumoniae ATCC 10813 0.25 0.008 (PSSP) CDC 1020 0.5 2.0 (PRSP) CDC 1199 0.25 1.0 (PRSP) CDC 1329 0.25 2.0 (PRSP) CDC 146 0.5 4.0 (PSRP) Open in a separate window a PSSP, penicillin-susceptible S. pneumoniae ; PRSP, penicillin-resistant S. pneumoniae .

Techniques:

Dose-response relationships for 72-hour dosing of MX-2401 against S. pneumoniae ATCC 10813 in the thighs and lungs of normal and neutropenic mice. The error bars represent standard deviations.

Journal: Antimicrobial Agents and Chemotherapy

Article Title: In Vivo Pharmacodynamics of New Lipopeptide MX-2401 ▿

doi: 10.1128/AAC.00238-10

Figure Lengend Snippet: Dose-response relationships for 72-hour dosing of MX-2401 against S. pneumoniae ATCC 10813 in the thighs and lungs of normal and neutropenic mice. The error bars represent standard deviations.

Article Snippet: The MICs were 2- to 8-fold lower for pneumococci than for staphylococci. table ft1 table-wrap mode="anchored" t5 TABLE 1. caption a7 Study organism MIC (μg/ml) MX-2401 Penicillin a S. aureus ATCC 29213 2.0 0.5 (MSSA) ATCC 33591 2.0 R (MRSA) ATCC 6538P 1.0 0.12 (MSSA) UW 31005 2.0 R (MSSA) UW 307109 2.0 R (MRSA) S. pneumoniae ATCC 10813 0.25 0.008 (PSSP) CDC 1020 0.5 2.0 (PRSP) CDC 1199 0.25 1.0 (PRSP) CDC 1329 0.25 2.0 (PRSP) CDC 146 0.5 4.0 (PSRP) Open in a separate window a PSSP, penicillin-susceptible S. pneumoniae ; PRSP, penicillin-resistant S. pneumoniae .

Techniques: